Meta-Analysis on Toric Intraocular Lens for Cataract and Corneal Astigmatism

Objective To clarify the effect of Toric intraocular lens (IOL) in the treatment of cataract and corneal astigmatism by meta-analysis. Methods The PubMed, EMBASE, Cochrane library, CNKI, Wanfang, and VIP database were searched for studies investigating the effect of Toric IOL in the treatment of cataract and corneal astigmatism. Meta-analysis was performed using RevMan 5.3 software to analyze the uncorrected distant visual acuity (UCDVA), best corrected distant visual acuity (BCDVA), and residual astigmatism between Toric IOL and traditional IOL. Results A total of 18 studies including 1 761 patients (1 923 eyes) were included. The pooled MD of -0.07(95%CI -0.10~ -0.04, P<0.000 1)showed that patients received Toric IOL implantation have better UCDVA. Pooled of seven studies evaluating the percentage of patients reaching UCDVA 20/25 revealed a OR of 0.32 (95%CI 0.24~0.43,P<0.000 1), suggesting patients with Toric IOL implantation have decreased risk of can not reach 20/25 UCDVA; in addition, the pooled of three studies reported a decreased risk patients with Toric IOL implantation in terms of can not reaching BCDVA 20/25 (OR=0.58,95%CI 0.41~1.01,P=0.05); at last, pooled analysis of fourteen studies revealed that patients with Toric IOL implantation have significantly improved corneal astigmatism (MD=-0.49,95%CI -0.69~-0.30, P<0.000 01). Conclusion Toric IOL is effective in the treatment of cataract and corneal astigmatism with ideal postoperative distant visual acuity and decreased degree of corneal astigmatism.